Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 2.998


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
HOXA6 3203 homeobox A6
HOXA7 3204 homeobox A7
HOXB6 3216 homeobox B6
HOXB7 3217 homeobox B7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXB6chr17_-_466823330.638.5e-03Click!
HOXA7chr7_-_271961630.381.5e-01Click!
HOXB7chr17_-_466879250.292.7e-01Click!
HOXA6chr7_-_271873670.224.2e-01Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_14086901 28.732 NFIB
nuclear factor I/B
chr3_+_159557745 16.163 SCHIP1
schwannomin interacting protein 1
chr2_+_102508377 15.917 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_+_159557649 14.235 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr3_+_158787040 13.762 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr2_+_102508333 13.412 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chrX_+_135251795 11.140 NM_001167819
FHL1
four and a half LIM domains 1
chr5_+_71502700 10.326 MAP1B
microtubule-associated protein 1B
chr7_-_27205123 10.033 HOXA9
homeobox A9
chr2_-_216259197 9.972 FN1
fibronectin 1
chr2_-_216241321 9.722 FN1
fibronectin 1
chr7_-_27205148 9.185 NM_152739
HOXA9
homeobox A9
chr9_+_97521930 9.144 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chrX_+_135278912 9.104 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr10_-_126716452 8.992 NM_022802
CTBP2
C-terminal binding protein 2
chrX_+_135251454 8.702 NM_001159704
FHL1
four and a half LIM domains 1
chr12_-_91576805 8.369 NM_001920
DCN
decorin
chr7_-_41742666 8.337 NM_002192
INHBA
inhibin, beta A
chr13_-_38172862 7.938 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr22_-_36236330 7.920 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr21_-_27253197 7.881 APP
amyloid beta (A4) precursor protein
chr22_-_36236264 7.730 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr22_-_36236421 7.650 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr18_-_53089722 7.588 NM_001243233
TCF4
transcription factor 4
chr5_-_168271852 7.520


chr12_-_91576579 7.029 DCN
decorin
chr1_+_183114214 6.837 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr3_-_149095458 6.712 TM4SF1
transmembrane 4 L six family member 1
chr3_-_149095517 6.647 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr3_-_149095413 6.632 TM4SF1
transmembrane 4 L six family member 1
chr4_+_169418167 6.330 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr3_-_149095333 6.236 TM4SF1
transmembrane 4 L six family member 1
chr1_+_84630014 6.112 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr2_-_175712276 6.043 NM_001206602
CHN1
chimerin (chimaerin) 1
chr3_+_157154579 6.002 NM_002852
PTX3
pentraxin 3, long
chr7_+_134464161 5.977 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr2_-_190927321 5.957 NM_005259
MSTN
myostatin
chr18_-_21891469 5.955 NM_001242508
OSBPL1A
oxysterol binding protein-like 1A
chr1_+_84630575 5.931 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr17_-_46682333 5.711 NM_018952
HOXB6
homeobox B6
chr7_+_134464417 5.695 CALD1
caldesmon 1
chr6_+_121756744 5.629 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr1_+_84630374 5.550 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_81771844 5.536 LPHN2
latrophilin 2
chr11_+_101983170 5.490 NM_001195045
YAP1
Yes-associated protein 1
chr5_+_34687663 5.369 NM_001145523
RAI14
retinoic acid induced 14
chrX_-_10535476 5.235 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr16_+_82660390 5.227 NM_001220488
NM_001220489
NM_001220490
NM_001220491
NM_001220492
NM_001257
CDH13





cadherin 13, H-cadherin (heart)





chr12_-_89745997 5.077 DUSP6
dual specificity phosphatase 6
chr19_-_50143350 5.038 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr11_-_27742224 5.035 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr3_+_135741576 4.970 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr2_-_55237255 4.920 NM_007008
RTN4
reticulon 4
chr7_-_27183225 4.913 NM_019102
HOXA5
homeobox A5
chr7_+_134576187 4.902 CALD1
caldesmon 1
chr2_-_190044330 4.899 NM_000393
COL5A2
collagen, type V, alpha 2
chr3_-_55515361 4.714 WNT5A
wingless-type MMTV integration site family, member 5A
chr2_+_170366211 4.669 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr7_+_102553343 4.631 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr5_-_39394423 4.608 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr10_-_92681025 4.552 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr11_+_69467210 4.533 CCND1
cyclin D1
chr2_-_151344145 4.482 NM_005168
RND3
Rho family GTPase 3
chr11_-_115088628 4.450 CADM1
cell adhesion molecule 1
chr12_-_89746244 4.447 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr7_+_134576150 4.446 NM_033139
NM_033140
CALD1

caldesmon 1

chr12_-_50616425 4.375 NM_001113547
LIMA1
LIM domain and actin binding 1
chr11_+_131240370 4.370 NM_001048209
NTM
neurotrimin
chr18_+_61554938 4.268 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr3_-_114478117 4.264 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr2_+_33359607 4.241 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr8_+_9953061 4.086 NM_001135671
NM_001199729
MSRA

methionine sulfoxide reductase A

chr10_+_17270257 3.897 NM_003380
VIM
vimentin
chr17_-_46622274 3.871 NM_002145
HOXB2
homeobox B2
chr15_+_96869156 3.826 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr9_-_13250313 3.826 NM_003829
MPDZ
multiple PDZ domain protein
chr1_+_151032866 3.798 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_78470593 3.769 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr1_+_151032880 3.733 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr2_-_31352489 3.708 NM_001253827
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr6_-_169654047 3.652 NM_003247
THBS2
thrombospondin 2
chr1_+_151032683 3.643 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_-_57045214 3.611 PPAP2B
phosphatidic acid phosphatase type 2B
chr4_+_55095263 3.599 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr13_-_110802708 3.576 COL4A1
collagen, type IV, alpha 1
chr1_-_86043932 3.515 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr12_-_89746238 3.499 DUSP6
dual specificity phosphatase 6
chr8_+_32504250 3.484 NM_013959
NRG1
neuregulin 1
chr1_-_57045235 3.444 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_123339178 3.376 MYLK
myosin light chain kinase
chr17_-_46687925 3.312 HOXB7
homeobox B7
chr2_-_55199894 3.299


chr7_-_107880492 3.237 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr13_-_45010937 3.149 TSC22D1
TSC22 domain family, member 1
chr5_+_140771482 3.128 NM_014004
NM_032088
PCDHGA8

protocadherin gamma subfamily A, 8

chr6_+_83072922 3.093 NM_006670
TPBG
trophoblast glycoprotein
chr7_-_107643330 3.073 NM_002291
LAMB1
laminin, beta 1
chr11_-_27741192 3.070 NM_001143807
BDNF
brain-derived neurotrophic factor
chr2_+_66662692 3.005 MEIS1
Meis homeobox 1
chr20_+_19870209 2.983 NM_018993
RIN2
Ras and Rab interactor 2
chr7_+_18535351 2.954 NM_001204145
NM_001204146
NM_014707
NM_178423
HDAC9



histone deacetylase 9



chr4_+_41700736 2.938 LIMCH1
LIM and calponin homology domains 1
chr20_+_11898536 2.928 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr3_+_35721115 2.890 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr3_-_187452669 2.889 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr8_-_122653493 2.876 NM_005328
HAS2
hyaluronan synthase 2
chr5_-_111091947 2.856 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr6_+_143929316 2.842 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr1_-_57045129 2.813 PPAP2B
phosphatidic acid phosphatase type 2B
chrX_+_114827818 2.799 NM_001136025
NM_001172335
PLS3

plastin 3

chr8_-_49833823 2.796 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr5_-_39424930 2.791 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_+_140743755 2.751 NM_018918
NM_032054
PCDHGA5

protocadherin gamma subfamily A, 5

chr1_+_100111430 2.747 NM_017734
PALMD
palmdelphin
chrX_-_10851808 2.745 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chrX_-_10645726 2.740 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr11_-_27723061 2.728 NM_170733
BDNF
brain-derived neurotrophic factor
chr5_-_121414011 2.691 NM_002317
LOX
lysyl oxidase
chr9_-_14398981 2.682 NM_001190738
NFIB
nuclear factor I/B
chr7_+_134464372 2.669 CALD1
caldesmon 1
chr4_-_40936640 2.663 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr13_+_102104941 2.657 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr15_+_96876568 2.606 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_+_84609941 2.592 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_105322056 2.591 NM_032148
SLC41A2
solute carrier family 41, member 2
chr8_-_18666295 2.585 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr4_-_186877869 2.581 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr9_-_117880411 2.568 NM_002160
TNC
tenascin C
chr12_-_71031174 2.553 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr18_+_72922725 2.550 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr18_+_33234532 2.488 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chrX_-_10544852 2.476 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr15_+_57511616 2.446 NM_207040
TCF12
transcription factor 12
chr17_-_46671322 2.438 HOXB5
homeobox B5
chr3_-_114790221 2.422 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr5_+_125695787 2.405 NM_001146319
GRAMD3
GRAM domain containing 3
chr2_+_66662516 2.389 NM_002398
MEIS1
Meis homeobox 1
chr8_+_70378858 2.373 NM_001128204
NM_015170
SULF1

sulfatase 1

chr1_-_193155723 2.371 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr12_-_53012332 2.350 NM_175068
KRT73
keratin 73
chr5_+_102201526 2.337 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr13_-_45011059 2.285 NM_006022
TSC22D1
TSC22 domain family, member 1
chr12_-_28124915 2.276 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr17_-_46688362 2.261 NM_004502
HOXB7
homeobox B7
chr10_-_29923900 2.255 NM_021738
SVIL
supervillin
chr8_-_18541441 2.251 PSD3
pleckstrin and Sec7 domain containing 3
chr20_+_9458460 2.245 PLCB4
phospholipase C, beta 4
chr12_+_81101407 2.241 NM_002469
MYF6
myogenic factor 6 (herculin)
chr2_-_211179765 2.239 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr12_+_54422193 2.210 NM_004503
HOXC6
homeobox C6
chr10_-_33623299 2.199 NRP1
neuropilin 1
chr13_-_45011389 2.198 NM_001243797
TSC22D1
TSC22 domain family, member 1
chr11_-_27722599 2.190 NM_001143808
NM_001143809
NM_001143810
NM_001143811
BDNF



brain-derived neurotrophic factor



chr16_+_82660573 2.176 CDH13
cadherin 13, H-cadherin (heart)
chr5_+_34684611 2.172 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr4_+_41614911 2.154 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr10_-_92680784 2.152 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr5_+_36606667 2.119 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_68697997 2.118 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr12_+_119616594 2.113 NM_014365
HSPB8
heat shock 22kDa protein 8
chr10_+_86131546 2.083 FAM190B
family with sequence similarity 190, member B
chr9_-_95244634 2.076 ASPN
asporin
chr17_-_39675078 2.072 NM_002275
KRT15
keratin 15
chr3_-_79817058 2.070 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_-_244006471 2.060 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr5_+_155753755 2.059 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chrX_-_13835187 2.037 GPM6B
glycoprotein M6B
chr6_-_134498973 2.027 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr14_+_85999464 1.999


chr16_+_7382750 1.982 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr3_-_99833348 1.982 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chrX_-_13835012 1.969 GPM6B
glycoprotein M6B
chr8_-_101936521 1.961 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr4_-_186733372 1.959 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr1_+_84647342 1.956 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_+_70405080 1.953 SULF1
sulfatase 1
chr3_-_114343052 1.953 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr3_+_132318980 1.950 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr4_-_159093523 1.950 FAM198B
family with sequence similarity 198, member B
chr6_+_21593963 1.945 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr14_-_69445978 1.922 ACTN1
actinin, alpha 1
chr6_-_169653922 1.922 THBS2
thrombospondin 2
chr6_-_46293628 1.916 NM_005822
RCAN2
regulator of calcineurin 2
chr5_+_36606456 1.903 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr9_-_95244750 1.903 NM_001193335
NM_017680
ASPN

asporin

chr21_+_30517897 1.889 C21orf7
chromosome 21 open reading frame 7
chr10_+_63661012 1.877 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr2_-_169103886 1.869 NM_013233
STK39
serine threonine kinase 39
chr14_-_75078669 1.866 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr4_+_169013687 1.862 NM_007193
ANXA10
annexin A10
chr1_-_57044980 1.860 PPAP2B
phosphatidic acid phosphatase type 2B
chr5_+_140753480 1.852 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6

chr8_+_94929991 1.847 NM_001161778
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_-_82395401 1.846 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr21_-_39870303 1.840 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr14_-_69445974 1.836 ACTN1
actinin, alpha 1
chr18_+_56530060 1.825 NM_018181
ZNF532
zinc finger protein 532
chr10_+_63808968 1.820 NM_001244638
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr17_-_46671043 1.816 NM_002147
HOXB5
homeobox B5
chr6_-_46825942 1.802 GPR116
G protein-coupled receptor 116

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.05 6.62e-11 GO:0007275 multicellular organismal development
2.18 7.65e-11 GO:0048731 system development
1.93 6.18e-10 GO:0032502 developmental process
1.76 6.54e-10 GO:0032501 multicellular organismal process
2.73 9.85e-10 GO:0009653 anatomical structure morphogenesis
2.03 1.52e-09 GO:0048856 anatomical structure development
2.40 3.99e-09 GO:0030154 cell differentiation
2.34 1.37e-08 GO:0048869 cellular developmental process
5.26 2.50e-07 GO:0061061 muscle structure development
3.25 8.22e-07 GO:0007155 cell adhesion
3.25 8.22e-07 GO:0022610 biological adhesion
6.10 1.09e-06 GO:0007517 muscle organ development
2.23 1.58e-06 GO:0048513 organ development
9.21 3.04e-05 GO:0048706 embryonic skeletal system development
3.77 3.07e-05 GO:0016477 cell migration
2.76 3.49e-05 GO:0048468 cell development
3.27 4.22e-05 GO:0009887 organ morphogenesis
2.81 5.63e-05 GO:0009888 tissue development
4.24 7.12e-05 GO:0001501 skeletal system development
3.27 7.87e-05 GO:0006928 cellular component movement
3.50 1.24e-04 GO:0048870 cell motility
3.50 1.24e-04 GO:0051674 localization of cell
2.67 1.98e-04 GO:0040011 locomotion
2.96 2.09e-04 GO:0045595 regulation of cell differentiation
19.50 4.29e-04 GO:0008038 neuron recognition
9.04 6.90e-04 GO:0007519 skeletal muscle tissue development
4.00 7.96e-04 GO:0001944 vasculature development
5.53 8.14e-04 GO:0009952 anterior/posterior pattern formation
2.15 8.64e-04 GO:0007399 nervous system development
8.73 9.46e-04 GO:0060538 skeletal muscle organ development
2.54 9.46e-04 GO:0022008 neurogenesis
3.93 1.00e-03 GO:0007389 pattern specification process
3.21 1.07e-03 GO:0072358 cardiovascular system development
3.21 1.07e-03 GO:0072359 circulatory system development
4.63 1.11e-03 GO:0003002 regionalization
3.17 1.33e-03 GO:0031175 neuron projection development
2.99 1.34e-03 GO:0048666 neuron development
4.05 1.36e-03 GO:0001568 blood vessel development
5.72 1.54e-03 GO:0060537 muscle tissue development
2.48 1.64e-03 GO:0050793 regulation of developmental process
3.13 1.71e-03 GO:0000904 cell morphogenesis involved in differentiation
9.61 1.84e-03 GO:0008037 cell recognition
2.84 2.04e-03 GO:0030030 cell projection organization
9.41 2.18e-03 GO:0048704 embryonic skeletal system morphogenesis
2.53 2.23e-03 GO:0048699 generation of neurons
2.71 3.14e-03 GO:0030182 neuron differentiation
5.31 3.41e-03 GO:0048562 embryonic organ morphogenesis
1.36 3.84e-03 GO:0050794 regulation of cellular process
5.74 4.16e-03 GO:0014706 striated muscle tissue development
5.63 5.00e-03 GO:0048705 skeletal system morphogenesis
5.03 6.03e-03 GO:0043062 extracellular structure organization
3.62 6.44e-03 GO:0051093 negative regulation of developmental process
1.81 6.82e-03 GO:0048523 negative regulation of cellular process
3.43 7.01e-03 GO:0043009 chordate embryonic development
2.78 7.53e-03 GO:0000902 cell morphogenesis
3.97 7.64e-03 GO:0045596 negative regulation of cell differentiation
3.41 7.71e-03 GO:0060429 epithelium development
3.39 8.47e-03 GO:0009792 embryo development ending in birth or egg hatching
5.20 1.09e-02 GO:0007156 homophilic cell adhesion
7.62 1.12e-02 GO:0051147 regulation of muscle cell differentiation
1.74 1.20e-02 GO:0048519 negative regulation of biological process
3.06 1.21e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
2.62 1.37e-02 GO:0009790 embryo development
3.01 1.47e-02 GO:0048812 neuron projection morphogenesis
2.64 1.83e-02 GO:0032989 cellular component morphogenesis
2.64 1.83e-02 GO:0042060 wound healing
3.50 1.86e-02 GO:0022603 regulation of anatomical structure morphogenesis
2.46 1.91e-02 GO:2000026 regulation of multicellular organismal development
3.30 2.15e-02 GO:0048598 embryonic morphogenesis
3.01 2.49e-02 GO:0007409 axonogenesis
2.90 2.54e-02 GO:0051094 positive regulation of developmental process
41.43 2.85e-02 GO:0016199 axon midline choice point recognition
1.30 4.73e-02 GO:0050789 regulation of biological process
3.82 4.74e-02 GO:0048568 embryonic organ development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
5.19 1.95e-08 GO:0005578 proteinaceous extracellular matrix
4.30 8.09e-07 GO:0031012 extracellular matrix
2.38 2.03e-04 GO:0044421 extracellular region part
6.20 2.94e-04 GO:0044420 extracellular matrix part
5.85 5.31e-04 GO:0030016 myofibril
5.48 1.01e-03 GO:0043292 contractile fiber
1.56 1.01e-03 GO:0071944 cell periphery
1.55 2.05e-03 GO:0005886 plasma membrane
5.47 2.74e-03 GO:0044449 contractile fiber part
1.79 1.31e-02 GO:0005576 extracellular region
4.14 1.42e-02 GO:0070161 anchoring junction
3.20 1.46e-02 GO:0015629 actin cytoskeleton
2.56 1.49e-02 GO:0030054 cell junction
4.19 2.73e-02 GO:0005912 adherens junction
5.14 3.09e-02 GO:0030017 sarcomere
2.16 3.50e-02 GO:0005615 extracellular space

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.90 8.80e-05 GO:0005509 calcium ion binding
2.88 1.02e-04 GO:0043565 sequence-specific DNA binding
2.45 2.34e-04 GO:0001071 nucleic acid binding transcription factor activity
2.45 2.34e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
3.67 4.54e-04 GO:0003779 actin binding
2.12 1.70e-02 GO:0030528 transcription regulator activity
2.50 3.45e-02 GO:0008092 cytoskeletal protein binding